Refined sugar depletes B-vitamins?

[RRM]

The good thing about white sugar is that it does not ... require any enzymatic digestion

Sugar is actively transported across cell membranes and its digestion does require brush-border enzymes

The topic of this thread is depletion of the B-vitamins due to sugar.
I meant to say that no B-vitamins (or other co-factors) are required for the enzymatic activity involved in the initial digestion of sucrose.

Initially, hydrolysis (performed by glycoside hydrolases) breaks down sucrose (the oxygen bridge)
into glucose and fructose (with the help of a water molecule).
Sucrose + water > glucose + fructose
This hydrolysis occurs in the stomach (accelerated by the gastric acidity) and the small intestine (accelerated by sucrase).

For the transportation of glucose across the apical membrane in the small intestine, sodium is required.
After uptake, for the actual use of energy, glucose and fructose enter glycolysis (glucose > pyruvate),
for which manganese is required (as a cofactor).
In the conversion of pyruvate into acetyl-CoA, vitamin B1 is required (TPP; a B1 derivative, also containing sulphur and nitrogen).

[djkvan]

Now we're talkin' some biochemistry!

[Rivera]

What's your thoughts on this article?
http://articles.mercola.com/sites/artic ... _DNL_art_1

[Oscar]

I have seen a video of this guy Lustig, where he explains his theory in (excruciating) detail. As usual with these kinds of theories he has some valid points, but then goes on to draw the wrong conclusions. On the surface he manages to paint a pretty convincing picture, but it doesn't hold up under close scrutiny.

[overkees]

What must be added is that fructose must be in a 1:1 ratio with glucose for optimal results. This is a logical consequence because fruits are often close to this ratio.

http://en.wikipedia.org/wiki/Fructose#Food_sources